Accutane (Isotretinoin)Brand Names: Accutane, Amnesteem, Claravis, Sotret
Related Medications: Acanya, Azelex, BenzaClin, Cleocin T, Declomycin, Differin Gel .1, Minocin, Minocin Capsules, Minocin Injection, Onexton, Plexion, Retin-A Micro, Solodyn
If patients have severe cystic or nodular acne that doesn’t respond to other available treatments, including benzoyl peroxide, they are often prescribed to try Accutane. Basically, this medication belongs to a group of drugs called retinoids, and it functions by reducing the production of sebum, or facial oil. It’s clear that its high amount may result in developing severe acne, and if this medical condition is left untreated, people may end up with permanent scars.
Accutane is a popular oral medicine taken to treat and prevent severe acne episodes, and it’s all about eliminating skin inflammation. Acne often targets teens, but it may affect adult patients, too. When it comes to its severe cases, there are some negative effects, including permanent scarring. Detailed mechanism of action of Accutane is still unknown, but there are suggestions that its use decreases acne by reducing sebum production. That’s why this medication is often used to treat severe acne cases resistant to other traditional treatments, such as drying agents, creams, oral and topical antibiotics. Usually, it takes up to 20 weeks for patients to end up with complete remission. However, its use is associated with serious adverse effects, including birth defects, so people can take Accutane only for severe and resistant acne, and they must be supervised by their doctors.
There are some common adverse effects associated with the use of this medicine, and they include:
Some patients may have joint ache, increased levels of triglycerides and cholesterol in their blood. Besides, there are certain psychiatric issues that may develop, including hallucinations, depression and even suicidal behaviors. Other serious side effects that may be the result of Accutane administration include:
In very rare cases this medicine results in brain swelling, and this health condition is characterized by headaches, vomiting, nausea and vision changes.
Nowadays Accutane is available in the form of capsules that come in different strengths, from 10 mg to 40 mg. When it comes to correct doses, the most common one is 0.5-2 mg per 1 kg taken on a daily basis, and it’s advisable to take pills with food to improve their absorption.
Patients should understand that this medication is closely connected with vitamin A, so that they can’t be taken together to avoid a number of unwanted symptoms. In addition, Accutane and any tetracycline treatment shouldn’t be given at the same time because this drug combination is associated with brain swelling. There are some other precautions that patients need to know, especially if they have allergic reactions, diabetes, high blood fats, psychiatric disorders, etc.